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Lactate Contributes to Glyceroneogenesis and Glyconeogenesis in Skeletal Muscle by Reversal of Pyruvate Kinase

Phosphoenolpyruvate (PEP) generated from pyruvate is required for de novo synthesis of glycerol and glycogen in skeletal muscle. One possible pathway involves synthesis of PEP from the citric acid cycle intermediates via PEP carboxykinase, whereas another could involve reversal of pyruvate kinase (P...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jin, Eunsook S., Sherry, A. Dean, Malloy, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683270/
https://ncbi.nlm.nih.gov/pubmed/26491014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689174
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