Pyruvate Dehydrogenase Kinase 4: Regulation by Thiazolidinediones and Implication in Glyceroneogenesis in Adipose Tissue

OBJECTIVE—Pyruvate dehydrogenase complex (PDC) serves as the metabolic switch between glucose and fatty acid utilization. PDC activity is inhibited by PDC kinase (PDK). PDC shares the same substrate, i.e., pyruvate, as glyceroneogenesis, a pathway controlling fatty acid release from white adipose ti...

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Detalhes bibliográficos
Main Authors: Cadoudal, Thomas, Distel, Emilie, Durant, Sylvie, Fouque, Françoise, Blouin, Jean-Marc, Collinet, Martine, Bortoli, Sylvie, Forest, Claude, Benelli, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518477/
https://ncbi.nlm.nih.gov/pubmed/18519799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0477
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