Pyruvate Dehydrogenase Kinase 4: Regulation by Thiazolidinediones and Implication in Glyceroneogenesis in Adipose Tissue

OBJECTIVE—Pyruvate dehydrogenase complex (PDC) serves as the metabolic switch between glucose and fatty acid utilization. PDC activity is inhibited by PDC kinase (PDK). PDC shares the same substrate, i.e., pyruvate, as glyceroneogenesis, a pathway controlling fatty acid release from white adipose ti...

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Autors principals: Cadoudal, Thomas, Distel, Emilie, Durant, Sylvie, Fouque, Françoise, Blouin, Jean-Marc, Collinet, Martine, Bortoli, Sylvie, Forest, Claude, Benelli, Chantal
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2008
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518477/
https://ncbi.nlm.nih.gov/pubmed/18519799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0477
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