Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B-cells

Because MYC plays a causal role in many human cancers, including those with hypoxic and nutrient-poor tumor microenvironments, we have determined the metabolic responses of a MYC-inducible human Burkitt lymphoma model P493 cell line to aerobic and hypoxic conditions, and to glucose deprivation, usin...

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Bibliografski detalji
Glavni autori: Le, Anne, Lane, Andrew N., Hamaker, Max, Bose, Sminu, Gouw, Arvin, Barbi, Joseph, Tsukamoto, Takashi, Rojas, Camilio J., Slusher, Barbara S., Zhang, Haixia, Zimmerman, Lisa J., Liebler, Daniel C., Slebos, Robbert J.C., Lorkiewicz, Pawel K., Higashi, Richard M., Fan, Teresa W. M., Dang, Chi V.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345194/
https://ncbi.nlm.nih.gov/pubmed/22225880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.12.009
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