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Mechanism of gating and partial agonist action in the glycine receptor

Ligand-gated ion channels mediate signal transduction at chemical synapses and transition between resting, open and desensitized states in response to neurotransmitter binding. Neurotransmitters that produce maximum open channel probabilities (Po) are full agonists whereas those that yield lower tha...

詳細記述

保存先:
書誌詳細
出版年:Cell
主要な著者: Yu, Jie, Zhu, Hongtao, Lape, Remigijus, Greiner, Timo, Du, Juan, Lü, Wei, Sivilotti, Lucia, Gouaux, Eric
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115384/
https://ncbi.nlm.nih.gov/pubmed/33567265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.01.026
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