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On the nature of partial agonism in the nicotinic receptor superfamily
Partial agonists are ligands which bind to receptors but produce only a small maximum response even at concentrations where all receptors are occupied. In the case of ligand-activated ion channels, it has been supposed ever since 1957 that partial agonists evoke a small response because they are ine...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629928/ https://ncbi.nlm.nih.gov/pubmed/18633353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07139 |
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