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Agonist and blocking actions of choline and tetramethylammonium on human muscle acetylcholine receptors
Choline has been used widely as an agonist for the investigation of gain-of-function mutants of the nicotinic acetylcholine receptor. It is useful because it behaves like a partial agonist. The efficacy of choline is difficult to measure because choline blocks the channel at concentrations about fou...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790248/ https://ncbi.nlm.nih.gov/pubmed/19752108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.176305 |
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