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Agonist and blocking actions of choline and tetramethylammonium on human muscle acetylcholine receptors

Choline has been used widely as an agonist for the investigation of gain-of-function mutants of the nicotinic acetylcholine receptor. It is useful because it behaves like a partial agonist. The efficacy of choline is difficult to measure because choline blocks the channel at concentrations about fou...

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Bibliografski detalji
Glavni autori: Lape, Remigijus, Krashia, Paraskevi, Colquhoun, David, Sivilotti, Lucia G
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790248/
https://ncbi.nlm.nih.gov/pubmed/19752108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.176305
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