Wird geladen...

On the nature of partial agonism in the nicotinic receptor superfamily

Partial agonists are ligands which bind to receptors but produce only a small maximum response even at concentrations where all receptors are occupied. In the case of ligand-activated ion channels, it has been supposed ever since 1957 that partial agonists evoke a small response because they are ine...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lape, Remigijus, Colquhoun, David, Sivilotti, Lucia G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629928/
https://ncbi.nlm.nih.gov/pubmed/18633353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07139
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!