Pyridostigmine improves cardiac function and rhythmicity through RyR2 stabilization and inhibition of STIM1‐mediated calcium entry in heart failure

Heart failure (HF) is characterized by asymmetrical autonomic balance. Treatments to restore parasympathetic activity in human heart failure trials have shown beneficial effects. However, mechanisms of parasympathetic‐mediated improvement in cardiac function remain unclear. The present study examine...

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Pubblicato in:J Cell Mol Med
Autori principali: Baine, Stephen, Bonilla, Ingrid, Belevych, Andriy, Stepanov, Andrei, Dorn, Lisa E., Terentyeva, Radmila, Terentyev, Dmitry, Accornero, Federica, Carnes, Cynthia A., Gyorke, Sandor
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107086/
https://ncbi.nlm.nih.gov/pubmed/33755308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16356
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