Pyridostigmine improves cardiac function and rhythmicity through RyR2 stabilization and inhibition of STIM1‐mediated calcium entry in heart failure

Heart failure (HF) is characterized by asymmetrical autonomic balance. Treatments to restore parasympathetic activity in human heart failure trials have shown beneficial effects. However, mechanisms of parasympathetic‐mediated improvement in cardiac function remain unclear. The present study examine...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Baine, Stephen, Bonilla, Ingrid, Belevych, Andriy, Stepanov, Andrei, Dorn, Lisa E., Terentyeva, Radmila, Terentyev, Dmitry, Accornero, Federica, Carnes, Cynthia A., Gyorke, Sandor
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107086/
https://ncbi.nlm.nih.gov/pubmed/33755308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16356
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