Muscarinic Stimulation Facilitates SR Ca Release by Modulating RyR2 Phosphorylation Through PKG and CaMKII

While the effects and the underlying mechanism of sympathetic stimulation on cardiac Ca handling are relatively well established both in health and disease, the modes of action and mechanisms of parasympathetic modulation are poorly defined. Here we demonstrate that parasympathetic stimulation initi...

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Опубликовано в: :Hypertension
Главные авторы: Ho, Hsiang-Ting, Belevych, Andriy E, Liu, Bin, Bonilla, Ingrid M., Radwański, Przemysław B., Kubasov, Igor V, Valdivia, Héctor H, Schober, Karsten, Carnes, Cynthia A, Györke, Sándor
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063706/
https://ncbi.nlm.nih.gov/pubmed/27647848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07666
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