Muscarinic Stimulation Facilitates SR Ca Release by Modulating RyR2 Phosphorylation Through PKG and CaMKII

While the effects and the underlying mechanism of sympathetic stimulation on cardiac Ca handling are relatively well established both in health and disease, the modes of action and mechanisms of parasympathetic modulation are poorly defined. Here we demonstrate that parasympathetic stimulation initi...

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Publicat a:Hypertension
Autors principals: Ho, Hsiang-Ting, Belevych, Andriy E, Liu, Bin, Bonilla, Ingrid M., Radwański, Przemysław B., Kubasov, Igor V, Valdivia, Héctor H, Schober, Karsten, Carnes, Cynthia A, Györke, Sándor
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063706/
https://ncbi.nlm.nih.gov/pubmed/27647848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07666
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