Muscarinic Stimulation Facilitates SR Ca Release by Modulating RyR2 Phosphorylation Through PKG and CaMKII

While the effects and the underlying mechanism of sympathetic stimulation on cardiac Ca handling are relatively well established both in health and disease, the modes of action and mechanisms of parasympathetic modulation are poorly defined. Here we demonstrate that parasympathetic stimulation initi...

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Bibliographic Details
Published in:Hypertension
Main Authors: Ho, Hsiang-Ting, Belevych, Andriy E, Liu, Bin, Bonilla, Ingrid M., Radwański, Przemysław B., Kubasov, Igor V, Valdivia, Héctor H, Schober, Karsten, Carnes, Cynthia A, Györke, Sándor
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063706/
https://ncbi.nlm.nih.gov/pubmed/27647848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07666
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