Alterations of Cytochrome P450s and UDP-Glucuronosyltransferases in Brain Under Diseases and Their Clinical Significances

Cytochrome P450s (CYPs) and UDP-glucuronosyltransferases (UGTs) are both greatly important metabolic enzymes in various tissues, including brain. Although expressions of brain CYPs and UGTs and their contributions to drug disposition are much less than liver, both CYPs and UGTs also mediate metaboli...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Sheng, Yun, Yang, Hanyu, Wu, Tong, Zhu, Liang, Liu, Li, Liu, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097730/
https://ncbi.nlm.nih.gov/pubmed/33967789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.650027
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