Alterations of Cytochrome P450s and UDP-Glucuronosyltransferases in Brain Under Diseases and Their Clinical Significances

Cytochrome P450s (CYPs) and UDP-glucuronosyltransferases (UGTs) are both greatly important metabolic enzymes in various tissues, including brain. Although expressions of brain CYPs and UGTs and their contributions to drug disposition are much less than liver, both CYPs and UGTs also mediate metaboli...

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Vydáno v:Front Pharmacol
Hlavní autoři: Sheng, Yun, Yang, Hanyu, Wu, Tong, Zhu, Liang, Liu, Li, Liu, Xiaodong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097730/
https://ncbi.nlm.nih.gov/pubmed/33967789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.650027
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