Alterations of Cytochrome P450s and UDP-Glucuronosyltransferases in Brain Under Diseases and Their Clinical Significances

Cytochrome P450s (CYPs) and UDP-glucuronosyltransferases (UGTs) are both greatly important metabolic enzymes in various tissues, including brain. Although expressions of brain CYPs and UGTs and their contributions to drug disposition are much less than liver, both CYPs and UGTs also mediate metaboli...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Sheng, Yun, Yang, Hanyu, Wu, Tong, Zhu, Liang, Liu, Li, Liu, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097730/
https://ncbi.nlm.nih.gov/pubmed/33967789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.650027
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