Intraneuronal APP/Aβ Trafficking and Plaque Formation in β‐Amyloid Precursor Protein and Presenilin‐1 Transgenic Mice

Neuropil deposition of β‐amyloid peptides Aβ40 and Aβ42 is believed to be the key event in the neurodegenerative processes of Alzheimer's disease (AD). Since Aβ seems to carry a transport signal that is required for axonal sorting of its precursor β‐amyloid precursor protein (APP), we studied t...

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Vydáno v:Brain Pathol
Hlavní autoři: Wirths, Oliver, Multhaup, Gerd, Czech, Christian, Feldmann, Nicole, Blanchard, Véronique, Tremp, Günter, Beyreuther, Konrad, Pradier, Laurent, Bayer, Thomas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095864/
https://ncbi.nlm.nih.gov/pubmed/12146796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2002.tb00442.x
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