Differential Expression of Utrophin‐A and ‐B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice

Utrophin (Utrn) is the autosomal homolog of dystrophin, the Duchene Muscular Dystrophy (DMD) locus product and of therapeutic interest, as its overexpression can compensate dystrophin's absence. Utrn is transcribed by Utrn‐A and ‐B promoters with mRNAs differing at their 5′ ends. However, previ...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Brain Pathol
Autori principali: Baby, Santhosh M., Bogdanovich, Sasha, Willmann, Gabriel, Basu, Utpal, Lozynska, Olga, Khurana, Tejvir S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2009
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095546/
https://ncbi.nlm.nih.gov/pubmed/19486009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00275.x
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