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Differential Expression of Utrophin‐A and ‐B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice

Utrophin (Utrn) is the autosomal homolog of dystrophin, the Duchene Muscular Dystrophy (DMD) locus product and of therapeutic interest, as its overexpression can compensate dystrophin's absence. Utrn is transcribed by Utrn‐A and ‐B promoters with mRNAs differing at their 5′ ends. However, previ...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: Baby, Santhosh M., Bogdanovich, Sasha, Willmann, Gabriel, Basu, Utpal, Lozynska, Olga, Khurana, Tejvir S.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095546/
https://ncbi.nlm.nih.gov/pubmed/19486009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00275.x
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