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Differential Expression of Utrophin‐A and ‐B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice

Utrophin (Utrn) is the autosomal homolog of dystrophin, the Duchene Muscular Dystrophy (DMD) locus product and of therapeutic interest, as its overexpression can compensate dystrophin's absence. Utrn is transcribed by Utrn‐A and ‐B promoters with mRNAs differing at their 5′ ends. However, previ...

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書目詳細資料
發表在:Brain Pathol
Main Authors: Baby, Santhosh M., Bogdanovich, Sasha, Willmann, Gabriel, Basu, Utpal, Lozynska, Olga, Khurana, Tejvir S.
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095546/
https://ncbi.nlm.nih.gov/pubmed/19486009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00275.x
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