Heregulin-induced Epigenetic Regulation of the Utrophin-A Promoter

Utrophin is the autosomal homolog of dystrophin, the product of the Duchenne’s muscular dystrophy (DMD) locus. Utrophin is of therapeutic interest since its overexpression can compensate dystrophin’s absence. Utrophin is enriched at neuromuscular junctions due to heregulin-mediated utrophin-A promot...

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Bibliographic Details
Main Authors: Basu, Utpal, Gyrd-Hansen, Mads, Baby, Santhosh M., Lozynska, Olga, Krag, Thomas O. B., Jensen, Claus J., Frödin, Morten, Khurana, Tejvir S.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699486/
https://ncbi.nlm.nih.gov/pubmed/17692845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.07.021
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