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Heregulin-induced Epigenetic Regulation of the Utrophin-A Promoter

Utrophin is the autosomal homolog of dystrophin, the product of the Duchenne’s muscular dystrophy (DMD) locus. Utrophin is of therapeutic interest since its overexpression can compensate dystrophin’s absence. Utrophin is enriched at neuromuscular junctions due to heregulin-mediated utrophin-A promot...

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Autors principals: Basu, Utpal, Gyrd-Hansen, Mads, Baby, Santhosh M., Lozynska, Olga, Krag, Thomas O. B., Jensen, Claus J., Frödin, Morten, Khurana, Tejvir S.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699486/
https://ncbi.nlm.nih.gov/pubmed/17692845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.07.021
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