Differential Expression of Utrophin‐A and ‐B Promoters in the Central Nervous System (CNS) of Normal and Dystrophic mdx Mice

Utrophin (Utrn) is the autosomal homolog of dystrophin, the Duchene Muscular Dystrophy (DMD) locus product and of therapeutic interest, as its overexpression can compensate dystrophin's absence. Utrn is transcribed by Utrn‐A and ‐B promoters with mRNAs differing at their 5′ ends. However, previ...

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Опубликовано в: :Brain Pathol
Главные авторы: Baby, Santhosh M., Bogdanovich, Sasha, Willmann, Gabriel, Basu, Utpal, Lozynska, Olga, Khurana, Tejvir S.
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2009
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095546/
https://ncbi.nlm.nih.gov/pubmed/19486009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00275.x
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