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Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice
Duchenne muscular dystrophy (DMD) is caused by mutations in dystrophin and the subsequent disruption of the dystrophin-associated protein complex (DAPC). Utrophin is a dystrophin homolog expressed at high levels in developing muscle that is an attractive target for DMD therapy. Here we show that the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021068/ https://ncbi.nlm.nih.gov/pubmed/21187385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013067108 |
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