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Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin(−/−) mice

Duchenne muscular dystrophy (DMD) patients lack dystrophin from birth; however, muscle weakness becomes apparent only at 3–5 years of age, which happens to coincide with the depletion of the muscle progenitor cell (MPC) pools. Indeed, MPCs isolated from older DMD patients demonstrate impairments in...

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Detalhes bibliográficos
Main Authors: Lu, Aiping, Poddar, Minakshi, Tang, Ying, Proto, Jonathan D., Sohn, Jihee, Mu, Xiaodong, Oyster, Nicholas, Wang, Bing, Huard, Johnny
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140461/
https://ncbi.nlm.nih.gov/pubmed/24781208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu194
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