Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin(−/−) mice

Duchenne muscular dystrophy (DMD) patients lack dystrophin from birth; however, muscle weakness becomes apparent only at 3–5 years of age, which happens to coincide with the depletion of the muscle progenitor cell (MPC) pools. Indeed, MPCs isolated from older DMD patients demonstrate impairments in...

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Main Authors: Lu, Aiping, Poddar, Minakshi, Tang, Ying, Proto, Jonathan D., Sohn, Jihee, Mu, Xiaodong, Oyster, Nicholas, Wang, Bing, Huard, Johnny
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140461/
https://ncbi.nlm.nih.gov/pubmed/24781208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu194
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