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Dystrophin and Utrophin “Double Knockout” Dystrophic Mice Exhibit a Spectrum of Degenerative Musculoskeletal Abnormalities
Duchenne muscular dystrophy (DMD) is a degenerative muscle disorder characterized by the lack of dystrophin expression at the sarcolemma of muscle fibers. In addition, DMD patients acquire osteopenia, fragility fractures, and scoliosis indicating that a deficiency in skeletal homeostasis coexists bu...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108902/ https://ncbi.nlm.nih.gov/pubmed/23097179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22236 |
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