Dystrophin and Utrophin “Double Knockout” Dystrophic Mice Exhibit a Spectrum of Degenerative Musculoskeletal Abnormalities

Duchenne muscular dystrophy (DMD) is a degenerative muscle disorder characterized by the lack of dystrophin expression at the sarcolemma of muscle fibers. In addition, DMD patients acquire osteopenia, fragility fractures, and scoliosis indicating that a deficiency in skeletal homeostasis coexists bu...

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Main Authors: Isaac, Christian, Wright, Adam, Usas, Arvydas, Li, Hongshuai, Tang, Ying, Mu, Xiaodong, Greco, Nicholas, Dong, Qing, Vo, Nam, Kang, James, Wang, Bing, Huard, Johnny
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108902/
https://ncbi.nlm.nih.gov/pubmed/23097179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22236
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