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RhoA/ROCK inhibition improves the beneficial effects of glucocorticoid treatment in dystrophic muscle: implications for stem cell depletion

Glucocorticoid treatment represents a standard palliative treatment for Duchenne muscular dystrophy (DMD) patients, but various adverse effects have limited this treatment. In an effort to understand the mechanism(s) by which glucocorticoids impart their effects on the dystrophic muscle, and potenti...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Mu, Xiaodong, Tang, Ying, Takayama, Koji, Chen, Wanqun, Lu, Aiping, Wang, Bing, Weiss, Kurt, Huard, Johnny
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886088/
https://ncbi.nlm.nih.gov/pubmed/28549178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx117
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