RhoA/ROCK inhibition improves the beneficial effects of glucocorticoid treatment in dystrophic muscle: implications for stem cell depletion

Glucocorticoid treatment represents a standard palliative treatment for Duchenne muscular dystrophy (DMD) patients, but various adverse effects have limited this treatment. In an effort to understand the mechanism(s) by which glucocorticoids impart their effects on the dystrophic muscle, and potenti...

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Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Mu, Xiaodong, Tang, Ying, Takayama, Koji, Chen, Wanqun, Lu, Aiping, Wang, Bing, Weiss, Kurt, Huard, Johnny
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886088/
https://ncbi.nlm.nih.gov/pubmed/28549178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx117
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