RhoA/ROCK inhibition improves the beneficial effects of glucocorticoid treatment in dystrophic muscle: implications for stem cell depletion

Glucocorticoid treatment represents a standard palliative treatment for Duchenne muscular dystrophy (DMD) patients, but various adverse effects have limited this treatment. In an effort to understand the mechanism(s) by which glucocorticoids impart their effects on the dystrophic muscle, and potenti...

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Vydáno v:Hum Mol Genet
Hlavní autoři: Mu, Xiaodong, Tang, Ying, Takayama, Koji, Chen, Wanqun, Lu, Aiping, Wang, Bing, Weiss, Kurt, Huard, Johnny
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886088/
https://ncbi.nlm.nih.gov/pubmed/28549178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx117
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