Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice

Duchenne Muscular Dystrophy (DMD) patients often suffer from both muscle wasting and osteoporosis. Our previous studies have revealed reduced regeneration potential in skeletal muscle and bone, concomitant with ectopic calcification of soft tissues in double knockout (dKO, dystrophin-/-; utrophin-/-...

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Опубликовано в: :Aging (Albany NY)
Главные авторы: Mu, Xiaodong, Lin, Chi-Yi, Hambright, William S., Tang, Ying, Ravuri, Sudheer, Lu, Aiping, Matre, Polina, Chen, Wanqun, Gao, Xueqin, Cui, Yan, Zhong, Ling, Wang, Bing, Huard, Johnny
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals 2020
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803538/
https://ncbi.nlm.nih.gov/pubmed/33361519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202413
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