Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice

Duchenne Muscular Dystrophy (DMD) patients often suffer from both muscle wasting and osteoporosis. Our previous studies have revealed reduced regeneration potential in skeletal muscle and bone, concomitant with ectopic calcification of soft tissues in double knockout (dKO, dystrophin-/-; utrophin-/-...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Mu, Xiaodong, Lin, Chi-Yi, Hambright, William S., Tang, Ying, Ravuri, Sudheer, Lu, Aiping, Matre, Polina, Chen, Wanqun, Gao, Xueqin, Cui, Yan, Zhong, Ling, Wang, Bing, Huard, Johnny
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803538/
https://ncbi.nlm.nih.gov/pubmed/33361519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202413
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