Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice

Duchenne Muscular Dystrophy (DMD) patients often suffer from both muscle wasting and osteoporosis. Our previous studies have revealed reduced regeneration potential in skeletal muscle and bone, concomitant with ectopic calcification of soft tissues in double knockout (dKO, dystrophin-/-; utrophin-/-...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Mu, Xiaodong, Lin, Chi-Yi, Hambright, William S., Tang, Ying, Ravuri, Sudheer, Lu, Aiping, Matre, Polina, Chen, Wanqun, Gao, Xueqin, Cui, Yan, Zhong, Ling, Wang, Bing, Huard, Johnny
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803538/
https://ncbi.nlm.nih.gov/pubmed/33361519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202413
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