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Identification of protein recognition elements within heparin chains using enzymatic foot-printing in solution and on-line SEC/MS

Understanding molecular mechanisms governing interactions of glycosaminoglycans (such as heparin) with proteins remains challenging due to their enormous structural heterogeneity. Commonly accepted approaches seek to reduce the structural complexity by searching for “binding epitopes” within the lim...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Anal Chem
Päätekijät: Niu, Chendi, Zhao, Yunlong, Bobst, Cedric E., Savinov, Sergey N., Kaltashov, Igor A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095033/
https://ncbi.nlm.nih.gov/pubmed/32347711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00115
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