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Towards better understanding of the heparin role in NETosis: feasibility of using native mass spectrometry to monitor interactions of neutrophil elastase with heparin oligomers

Neutrophil elastase is a serine protease released by neutrophils, and its dysregulation has been associated with a variety of debilitating pathologies, most notably cystic fibrosis. This protein is also a prominent component of the so-called neutrophil extracellular traps (NETs), whose formation is...

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Dades bibliogràfiques
Publicat a:Int J Mass Spectrom
Autors principals: Niu, Chendi, Du, Yi, Kaltashov, Igor A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939139/
https://ncbi.nlm.nih.gov/pubmed/33692650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2021.116550
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