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Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to heparins, characterized by thrombocytopenia and often severe thrombosis with high morbidity and mortality. HIT is mediated by IgG antibodies against heparin/platelet factor 4 antigenic complexes. These complexes are th...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428879/ https://ncbi.nlm.nih.gov/pubmed/30899022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09160-7 |
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