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A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

Neutrophils contain granules loaded with antimicrobial proteins and are regarded as impermeable organelles that deliver cargo via membrane fusion. However, during the formation of neutrophil extracellular traps (NETs), neutrophil elastase (NE) translocates from the granules to the nucleus via an unk...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Metzler, Kathleen D., Goosmann, Christian, Lubojemska, Aleksandra, Zychlinsky, Arturo, Papayannopoulos, Venizelos
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471680/
https://ncbi.nlm.nih.gov/pubmed/25066128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.044
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