A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

Neutrophils contain granules loaded with antimicrobial proteins and are regarded as impermeable organelles that deliver cargo via membrane fusion. However, during the formation of neutrophil extracellular traps (NETs), neutrophil elastase (NE) translocates from the granules to the nucleus via an unk...

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Vydáno v:Cell Rep
Hlavní autoři: Metzler, Kathleen D., Goosmann, Christian, Lubojemska, Aleksandra, Zychlinsky, Arturo, Papayannopoulos, Venizelos
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471680/
https://ncbi.nlm.nih.gov/pubmed/25066128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.044
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