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A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

Neutrophils contain granules loaded with antimicrobial proteins and are regarded as impermeable organelles that deliver cargo via membrane fusion. However, during the formation of neutrophil extracellular traps (NETs), neutrophil elastase (NE) translocates from the granules to the nucleus via an unk...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Metzler, Kathleen D., Goosmann, Christian, Lubojemska, Aleksandra, Zychlinsky, Arturo, Papayannopoulos, Venizelos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471680/
https://ncbi.nlm.nih.gov/pubmed/25066128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.06.044
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