Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

The granule enzyme myeloperoxidase (MPO) plays an important role in neutrophil antimicrobial responses. However, the severity of immunodeficiency in patients carrying mutations in MPO is variable. Serious microbial infections, especially with Candida species, have been observed in a subset of comple...

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Detalhes bibliográficos
Main Authors: Metzler, Kathleen D., Fuchs, Tobias A., Nauseef, William M., Reumaux, Dominique, Roesler, Joachim, Schulze, Ilka, Wahn, Volker, Papayannopoulos, Venizelos, Zychlinsky, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035083/
https://ncbi.nlm.nih.gov/pubmed/20974672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-290171
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