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Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
Neutrophils release decondensed chromatin termed neutrophil extracellular traps (NETs) to trap and kill pathogens extracellularly. Reactive oxygen species are required to initiate NET formation but the downstream molecular mechanism is unknown. We show that upon activation, neutrophil elastase (NE)...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003309/ https://ncbi.nlm.nih.gov/pubmed/20974816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006052 |
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