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Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity

Accumulation of amyloid beta peptides is thought to initiate the pathogenesis of Alzheimer's disease. However, the precise mechanisms mediating their neurotoxicity are unclear. Our microarray analyses show that, in Drosophila models of amyloid beta 42 toxicity, genes involved in the unfolded pr...

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Detalhes bibliográficos
Publicado no:Brain Commun
Main Authors: Niccoli, Teresa, Kerr, Fiona, Snoeren, Inge, Fabian, Daniel, Aleyakpo, Benjamin, Ivanov, Dobril, Sofola-Adesakin, Oyinkan, Cryar, Adam, Adcott, Jennifer, Thornton, Janet, Partridge, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093921/
https://ncbi.nlm.nih.gov/pubmed/33977265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcab053
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