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Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity

Accumulation of amyloid beta peptides is thought to initiate the pathogenesis of Alzheimer's disease. However, the precise mechanisms mediating their neurotoxicity are unclear. Our microarray analyses show that, in Drosophila models of amyloid beta 42 toxicity, genes involved in the unfolded pr...

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Dettagli Bibliografici
Pubblicato in:Brain Commun
Autori principali: Niccoli, Teresa, Kerr, Fiona, Snoeren, Inge, Fabian, Daniel, Aleyakpo, Benjamin, Ivanov, Dobril, Sofola-Adesakin, Oyinkan, Cryar, Adam, Adcott, Jennifer, Thornton, Janet, Partridge, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093921/
https://ncbi.nlm.nih.gov/pubmed/33977265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcab053
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