pGluAβ increases accumulation of Aβ in vivo and exacerbates its toxicity

Several species of β-amyloid peptides (Aβ) exist as a result of differential cleavage from amyloid precursor protein (APP) to yield various C-terminal Aβ peptides. Several N-terminal modified Aβ peptides have also been identified in Alzheimer’s disease (AD) brains, the most common of which is pyrogl...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Sofola-Adesakin, Oyinkan, Khericha, Mobina, Snoeren, Inge, Tsuda, Leo, Partridge, Linda
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055666/
https://ncbi.nlm.nih.gov/pubmed/27717375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0380-x
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