Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease

The greatest risk factor for Alzheimer's disease (AD) is age, and changes in the ageing nervous system are likely contributors to AD pathology. Amyloid beta (Aβ) accumulation, which occurs as a result of the amyloidogenic processing of amyloid precursor protein (APP), is thought to initiate the...

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Autores principales: Sofola-Adesakin, Oyinkan, Castillo-Quan, Jorge I., Rallis, Charalampos, Tain, Luke S., Bjedov, Ivana, Rogers, Iain, Li, Li, Martinez, Pedro, Khericha, Mobina, Cabecinha, Melissa, Bähler, Jürg, Partridge, Linda
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115666/
https://ncbi.nlm.nih.gov/pubmed/25126078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00190
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