Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease

The greatest risk factor for Alzheimer's disease (AD) is age, and changes in the ageing nervous system are likely contributors to AD pathology. Amyloid beta (Aβ) accumulation, which occurs as a result of the amyloidogenic processing of amyloid precursor protein (APP), is thought to initiate the...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sofola-Adesakin, Oyinkan, Castillo-Quan, Jorge I., Rallis, Charalampos, Tain, Luke S., Bjedov, Ivana, Rogers, Iain, Li, Li, Martinez, Pedro, Khericha, Mobina, Cabecinha, Melissa, Bähler, Jürg, Partridge, Linda
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2014
Θέματα:
Neuroscience
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115666/
https://ncbi.nlm.nih.gov/pubmed/25126078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00190
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