Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity

Accumulation of amyloid beta peptides is thought to initiate the pathogenesis of Alzheimer's disease. However, the precise mechanisms mediating their neurotoxicity are unclear. Our microarray analyses show that, in Drosophila models of amyloid beta 42 toxicity, genes involved in the unfolded pr...

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Vydáno v:Brain Commun
Hlavní autoři: Niccoli, Teresa, Kerr, Fiona, Snoeren, Inge, Fabian, Daniel, Aleyakpo, Benjamin, Ivanov, Dobril, Sofola-Adesakin, Oyinkan, Cryar, Adam, Adcott, Jennifer, Thornton, Janet, Partridge, Linda
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093921/
https://ncbi.nlm.nih.gov/pubmed/33977265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcab053
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