Synchrotron-Based X-Ray Fluorescence Microscopy Reveals Accumulation of Polymyxins in Single Human Alveolar Epithelial Cells

Intravenous administration of the last-line polymyxins results in poor drug exposure in the lungs and potential nephrotoxicity, whereas inhalation therapy offers better pharmacokinetics/pharmacodynamics for pulmonary infections by delivering the antibiotic directly to the infection site. However, po...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Azad, Mohamad A. K., Zhang, Shuo, Li, Jiayao, Kim, Yeonuk, Yu, Heidi H., Fulcher, Alex J., Howard, Daryl L., de Jonge, Martin D., James, Simon A., Roberts, Kade D., Velkov, Tony, Fu, Jing, Zhou, Qi Tony, Li, Jian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2021
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092916/
https://ncbi.nlm.nih.gov/pubmed/33649114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02314-20
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items