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Intracellular localization of polymyxins in human alveolar epithelial cells

BACKGROUND: Current inhaled polymyxin therapy is empirical and often large doses are administered, which can lead to pulmonary adverse effects. There is a dearth of information on the mechanisms of polymyxin-induced lung toxicity and their intracellular localization in lung epithelial cells. OBJECTI...

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Bibliografiske detaljer
Udgivet i:J Antimicrob Chemother
Main Authors: Ahmed, Maizbha U, Velkov, Tony, Zhou, Qi Tony, Fulcher, Alex J, Callaghan, Judy, Zhou, Fanfan, Chan, Kim, Azad, Mohammad A K, Li, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293086/
https://ncbi.nlm.nih.gov/pubmed/30357331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky409
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