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Polymyxin-Induced Cell Death of Human Macrophage-Like THP-1 and Neutrophil-Like HL-60 Cells Associated with the Activation of Apoptotic Pathways

Innate immunity is crucial for the host to defend against infections, and understanding the effect of polymyxins on innate immunity is important for optimizing their clinical use. In this study, we investigated the potential toxicity of polymyxins on human macrophage-like THP-1 and neutrophil-like H...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Fathalla, Ahmed M., Chow, Seong H., Naderer, Thomas, Zhou, Qi Tony, Velkov, Tony, Azad, Mohammad A. K., Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449205/
https://ncbi.nlm.nih.gov/pubmed/32660985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00013-20
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