HepatocyteGHR/STAT5b Signaling Protects Against Liver Injury in NAFLD/NASH Mice Models Independent of Steatosis

Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of pathologies ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) that can lead to cirrhosis and hepatocellular carcinoma. Clinical and mouse studies indicate GH-signaling is reduced in NAFLD. We reported that chow-fe...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: del Río-Moreno, Mercedes, Vazquez-Borrego, Mari C, Mahmood, Mariyah, Sarmento-Cabral, Andre, Guzman, Grace, Subbaiah, Papasani V, Cordoba-Chacon, Jose, Kineman, Rhonda Denise
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Adipose Tissue, Appetite, and Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090165/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.096
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