Lanean...

Cytosolic DNA sensing by cGAS: regulation, function, and human diseases

Sensing invasive cytosolic DNA is an integral component of innate immunity. cGAS was identified in 2013 as the major cytosolic DNA sensor that binds dsDNA to catalyze the synthesis of a special asymmetric cyclic-dinucleotide, 2′3′-cGAMP, as the secondary messenger to bind and activate STING for subs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Signal Transduct Target Ther
Egile Nagusiak: Yu, Le, Liu, Pengda
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085147/
https://ncbi.nlm.nih.gov/pubmed/33927185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00554-y
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!