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The cytosolic DNA-sensing cGAS-STING pathway in cancer

The recognition of DNA as an immune stimulatory molecule is an evolutionarily conserved mechanism to initiate rapid innate immune response against microbial pathogens. Recently, the cGAS-STING pathway has been discovered as an important DNA sensing machinery in innate immunity and viral defense. Rec...

詳細記述

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書誌詳細
出版年:Cancer Discov
主要な著者: Kwon, John, Bakhoum, Samuel F.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7151642/
https://ncbi.nlm.nih.gov/pubmed/31852718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0761
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