Spontaneous Formation of β-sheet Nano-barrels during the Early Aggregation of Alzheimer’s Amyloid Beta

Soluble low-molecular-weight oligomers formed during the early aggregation of amyloid peptides have been hypothesized as a major toxic species of amyloidogenesis. Herein, we performed the first synergic in silico, in vitro and in vivo validations of the structure, dynamics and toxicity of Aβ42 oligo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nano Today
Päätekijät: Sun, Yunxiang, Kakinen, Aleksandr, Wan, Xulin, Moriarty, Niamh, Hunt, Cameron P.J., Li, Yuhuan, Andrikopoulos, Nicholas, Nandakumar, Aparna, Davis, Thomas P., Parish, Clare L., Song, Yang, Ke, Pu Chun, Ding, Feng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081394/
https://ncbi.nlm.nih.gov/pubmed/33936250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nantod.2021.101125
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