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Amyloid Aggregation under the Lens of Liquid-Liquid Phase Separation

Increasing experiments suggest that amyloid peptides can undergo liquid-liquid phase separation (LLPS) before the formation of amyloid fibrils. However, the exact role of LLPS in amyloid aggregation at the molecular level remains elusive. Here, we investigated the LLPS and amyloid fibrillization of...

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Publicat a:J Phys Chem Lett
Autors principals: Xing, Yanting, Nandakumar, Aparna, Kakinen, Aleksandr, Sun, Yunxiang, Davis, Thomas P., Ke, Pu Chun, Ding, Feng
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855599/
https://ncbi.nlm.nih.gov/pubmed/33356290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.0c02567
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