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Lysophosphatidylcholine modulates the aggregation of human islet amyloid polypeptide

Amyloid aggregation of human islet amyloid polypeptide (IAPP) is a hallmark of type 2 diabetes (T2D), a metabolic disease and a global epidemic. Although IAPP is synthesized in pancreatic β-cells, its fibrils and plaques are found in the extracellular space indicating a causative transmembrane proce...

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Detalhes bibliográficos
Publicado no:Phys Chem Chem Phys
Main Authors: Xing, Yanting, Pilkington, Emily H., Wang, Miaoyi, Nowell, Cameron J., Kakinen, Aleksandr, Sun, Yunxiang, Wang, Bo, Davis, Thomas P., Ding, Feng, Ke, Pu Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901975/
https://ncbi.nlm.nih.gov/pubmed/29115353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cp06670h
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